Yokley R A, Cheung M W
Development Resources/Chemical Support Department, Novartis Crop Protection, Inc., Greensboro, North Carolina 27419, USA.
J Agric Food Chem. 2000 Oct;48(10):4500-7. doi: 10.1021/jf991100v.
A multiresidue method is reported for the determination of atrazine and its dealkylated chlorotriazine metabolites in water. Water samples are buffered to pH 10 and partitioned in ethyl acetate. Final analysis is accomplished using gas chromatography/mass selective detection (GC/MSD) in the selected ion monitoring (SIM) mode. The limit of detection (LOD) is 0.050 ng and the limit of quantification (LOQ) is 0.10 ppb for 2-chloro-4-(ethylamino)-6-(isopropylamino)-s-triazine (atrazine), 2-amino-4-chloro-6-(isopropylamino)-s-triazine (G-30033), 2-amino-4-chloro-6-(ethylamino)-s-triazine (G-28279), and 2, 4-diamino-6-chloro-s-triazine (G-28273). The mean procedural recoveries were 90, 92, 98, and 85% and the standard deviations were 12, 13, 16, and 20% for atrazine, G-30033, G-28279, and G-28273, respectively (n = 30). The study was conducted under U.S. EPA FIFRA Good Laboratory Practice Guidelines 40 CFR 160 for method validation. The reported procedure accounts for residues of G-28273 in water that are not included in EPA Method 507.
本文报道了一种用于测定水中莠去津及其脱烷基氯代三嗪代谢物的多残留方法。水样缓冲至pH 10后用乙酸乙酯进行液液萃取。最终分析采用气相色谱/质谱选择性检测（GC/MSD）的选择离子监测（SIM）模式完成。对于2-氯-4-（乙氨基）-6-（异丙氨基）-均三嗪（莠去津）、2-氨基-4-氯-6-（异丙氨基）-均三嗪（G-30033）、2-氨基-4-氯-6-（乙氨基）-均三嗪（G-28279）和2,4-二氨基-6-氯-均三嗪（G-28273），检测限（LOD）为0.050 ng，定量限（LOQ）为0.10 ppb。莠去津、G-30033、G-28279和G-28273的平均方法回收率分别为90%、92%、98%和85%，标准偏差分别为12%、13%、16%和20%（n = 30）。该研究是根据美国环境保护局联邦杀虫剂、杀菌剂和杀鼠剂法案（FIFRA）良好实验室规范指南40 CFR 160进行方法验证的。所报道的方法涵盖了美国环境保护局方法507未包括在内的水中G-28273的残留量。
