Huang Sung-Ben, Mayer Thomas J, Yokley Robert A, Perez Rolando
Analytical Resources Group, Syngenta Crop Protection, Inc., 410 Swing Road, P.O. Box 18300, Greensboro, North Carolina 27419-8300, USA.
J Agric Food Chem. 2006 Feb 8;54(3):713-9. doi: 10.1021/jf052968q.
A method is reported for the determination of atrazine, simazine, and their respective dealkylated chlorotriazine metabolites in ground, surface, and finished drinking water. Water samples are diluted 1:4 in an injection vial prior to analysis using liquid chromatography/electrospray ionization-mass spectrometry/mass spectrometry (LC/ESI-MS/MS). The lower limit of method validation is 0.10 microg/L (ppb) for 2-chloro-4-(ethylamino)-6-isopropylamino)-s-triazine (atrazine, G-30027), 2-chloro-4, 6-(diethylamino)-s-triazine (simazine, G-27692), 2-amino-4-chloro-6-(isopropylamino)-s-triazine (deethylatrazine, DEA, or G-30033), 2-amino-4-chloro-6-(ethylamino)-s-triazine (deisopropylatrazine, DIA, or G-28279), and 2,4-diamino-6-chloro-s-triazine (didealkylatrazine, DDA, or G-28273). The overall mean procedural recoveries (and % relative standard deviations) for atrazine, simazine, DEA, DIA, and DDA are 98 (4.4), 102 (3.6), 99 (4.8), 103 (4.0), and 109% (4.8%), respectively, in finished drinking water; 108 (2.7), 104 (5.4), 113 (4.5), 111 (5.2), and 105% (5.3%), respectively, in groundwater; and 96 (6.9), 103 (4.2), 102 (4.4), 102 (5.2), and 102% (8.2%), respectively, in surface water. The method validation was conducted under U.S. EPA FIFRA Good Laboratory Practice Guidelines 40 CFR 160.
本文报道了一种测定地下水、地表水和成品饮用水中阿特拉津、西玛津及其各自的脱烷基氯代三嗪代谢物的方法。在使用液相色谱/电喷雾电离-质谱/质谱（LC/ESI-MS/MS）进行分析之前，将水样在进样瓶中按1:4稀释。该方法验证的下限为：2-氯-4-（乙氨基）-6-（异丙氨基）-s-三嗪（阿特拉津，G-30027）、2-氯-4,6-（二乙氨基）-s-三嗪（西玛津，G-27692）、2-氨基-4-氯-6-（异丙氨基）-s-三嗪（去乙基阿特拉津，DEA，或G-30033）、2-氨基-4-氯-6-（乙氨基）-s-三嗪（去异丙基阿特拉津，DIA，或G-28279）以及2,4-二氨基-6-氯-s-三嗪（去二烷基阿特拉津，DDA，或G-28273）均为0.10微克/升（ppb）。在成品饮用水中，阿特拉津、西玛津、DEA、DIA和DDA的总体平均程序回收率（及相对标准偏差百分比）分别为98（4.4）、102（3.6）、99（4.8）、103（4.0）和109%（4.8%）；在地下水中分别为108（2.7）、104（5.4）、113（4.5）、111（5.2）和105%（5.3%）；在地表水中分别为96（6.9）、103（4.2）、102（4.4）、102（5.2）和102%（8.2%）。该方法验证是根据美国环保署《联邦杀虫剂、杀菌剂和杀鼠剂法案》良好实验室规范指南40 CFR 160进行的。
