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超声引导下注射凝血酶治疗医源性股动脉假性动脉瘤

Treatment of iatrogenic femoral artery pseudoaneurysms using ultrasound-guided injection of thrombin.

作者信息

Hughes M J, McCall J M, Nott D M, Padley S P

机构信息

Department of Radiology, Chelsea and Westminster Hospital, London, UK.

出版信息

Clin Radiol. 2000 Oct;55(10):749-51. doi: 10.1053/crad.2000.0516.

Abstract

AIM

To evaluate the use of ultrasound-guided percutaneous injection of thrombin for treatment of femoral artery pseudoaneurysms.

METHOD

Nine patients with a confirmed femoral false aneurysm were included in the study. 0.5-1 ml of a 2000 U/ml solution of activated bovine thrombin was injected under ultrasound visualization into the neck of the aneurysm to induce thrombosis. The parent artery and adjacent major vessels were checked during and after the procedure to exclude propagation of thrombus. A check ultrasound examination was undertaken on the following day.

RESULTS

Eight patients were successfully treated by a single injection. One patient required a second injection due to recurrence of their pseudoaneurysm 4 days after the initial treatment. The procedure was well tolerated in all cases and no complications were encountered.

CONCLUSION

This small series provides further evidence that ultrasound-guided thrombin injection is a promising new method for the treatment of femoral false aneurysms.Hughes, M. J. et al. (2000). Clinical Radiology55, 749-751.

摘要

目的

评估超声引导下经皮注射凝血酶治疗股动脉假性动脉瘤的应用。

方法

9例确诊为股动脉假性动脉瘤的患者纳入本研究。在超声引导下,将0.5 - 1毫升2000 U/毫升的活化牛凝血酶溶液注入动脉瘤颈部以诱导血栓形成。在操作过程中和操作后检查供血动脉和相邻主要血管,以排除血栓扩散。次日进行超声复查。

结果

8例患者经单次注射成功治疗。1例患者因初次治疗4天后假性动脉瘤复发而需要第二次注射。所有病例对该操作耐受性良好,未出现并发症。

结论

这个小样本系列进一步证明,超声引导下注射凝血酶是一种有前景的治疗股动脉假性动脉瘤的新方法。休斯,M. J. 等人(2000年)。《临床放射学》55卷,第749 - 751页。

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