Scuccimarri R, Azouz E M, Duffy K N, Fassier F, Duffy C M
Division of Rheumatology, Montreal Children's Hospital, Montreal, Quebec, Canada.
Ann Rheum Dis. 2000 Nov;59(11):864-9. doi: 10.1136/ard.59.11.864.
Osteochondrodysplasias are a heterogeneous group of genetic skeletal dysplasias. Patients with these diseases commonly develop an early degenerative arthritis or osteoarthritis. Occasional observations of inflammatory arthritis have been made in this population but such observations are based on clinical grounds alone without confirmatory imaging studies. Four patients followed up in a paediatric rheumatology clinic with three different skeletal dysplasias, who had both clinical and radiological evidence of an inflammatory arthritis and coexistent degenerative arthritis, are described.
骨软骨发育异常是一组遗传性骨骼发育异常的异质性疾病。患有这些疾病的患者通常会早期发展为退行性关节炎或骨关节炎。在这一人群中偶尔观察到炎症性关节炎，但此类观察仅基于临床依据，并无影像学研究的证实。本文描述了在一家儿科风湿病诊所随访的4例患者，他们患有三种不同的骨骼发育异常，同时具备炎症性关节炎和并存的退行性关节炎的临床及影像学证据。
