Byrd R B, Fisk D E, Roethe R A, Glover J N, Wooster L D, Wilder N J
Chest. 1979 Aug;76(2):136-9. doi: 10.1378/chest.76.2.136.
Tuberculosis in Oriental immigrants is likely to be resistant to therapy with certain drugs. In 73 military dependents with positive cultures for tuberculosis who immigrated from six Asian countries, the tuberculosis was found to be resistant to isoniazid in 58 percent (42 patients), to streptomycin in 36 percent (26 patients), to p-amino-salicylic acid in 14 percent (ten patients), to rifampin in 7 percent (five patients), and to ethambutol in 7 percent (five patients). Despite the presence of drug-resistant organisms and often extensive disease, negative cultures were attained in all but one patient. Consideration of the high incidence of drug-resistant tuberculosis should be made in planning a program of treatment for these patients. Recognition of cultural differences may also be of value in the successful treatment of this difficult group of patients.
东方移民中的结核病可能对某些药物治疗有耐药性。在73名从六个亚洲国家移民来的结核培养阳性的军人家属中，发现结核病对异烟肼耐药的占58%（42例患者），对链霉素耐药的占36%（26例患者），对对氨基水杨酸耐药的占14%（10例患者），对利福平耐药的占7%（5例患者），对乙胺丁醇耐药的占7%（5例患者）。尽管存在耐药菌且疾病往往广泛，但除1例患者外，所有患者的培养结果均转为阴性。在为这些患者制定治疗方案时，应考虑耐药结核病的高发病率。认识到文化差异对于成功治疗这一困难患者群体也可能具有价值。
