Brandes A A, Pasetto L M, Vastola F, Monfardini S
Department of Medical Oncology, Azienda Ospedale-Università, Padova, Italy.
Oncology. 2000 Sep;59(3):181-6. doi: 10.1159/000012158.
The incidence of central nervous system neoplasias ranges from 3.8 to 5.1 cases per 100,000 inhabitants. First-line treatment of brain tumors consists of surgery associated with radiotherapy, and followed or not by chemotherapy. When used as an adjuvant therapy after surgery and radiotherapy, chemotherapy prolongs the time to progression and the median survival time. At relapse, chemotherapy is the common therapeutic approach. In recent years, new drugs for the treatment of brain tumors have been tested, and some of them, such as temozolomide, are very promising.
中枢神经系统肿瘤的发病率为每10万居民中有3.8至5.1例。脑肿瘤的一线治疗包括手术联合放疗，之后是否进行化疗视情况而定。当化疗作为手术和放疗后的辅助治疗时，可延长疾病进展时间和中位生存期。复发时，化疗是常用的治疗方法。近年来，已对治疗脑肿瘤的新药进行了测试，其中一些药物，如替莫唑胺，前景十分广阔。
