Ramsey D J, Schey S A
Department of Haematology, Guy's Hospital, London, UK.
Br J Haematol. 2000 Sep;110(4):894-6. doi: 10.1046/j.1365-2141.2000.02282.x.
Bone marrow or stem cell transplantation is an established therapy for haematological malignancies. We report a cytomegalovirus (CMV) IgG +ve 56-year-old patient who underwent autologous rescue with CD34(+) selected peripheral blood stem cells as part of consolidation therapy for multiple myeloma and subsequently developed CMV colitis. In contrast to infection secondary to human immunodeficiency virus (HIV), CMV colitis has not previously been described in this context. We discuss this case and issues arising from it related to the use of CD34+ selected stem cells for transplantation.
骨髓或干细胞移植是血液系统恶性肿瘤的一种既定治疗方法。我们报告了一名56岁的巨细胞病毒（CMV）IgG阳性患者，该患者接受了经CD34(+)选择的外周血干细胞自体挽救治疗，作为多发性骨髓瘤巩固治疗的一部分，随后发生了CMV结肠炎。与人类免疫缺陷病毒（HIV）继发感染不同，此前尚未有关于在这种情况下发生CMV结肠炎的描述。我们讨论了该病例以及由此产生的与使用经CD34+选择的干细胞进行移植相关的问题。
