精甲霜灵原药中杂质的鉴定

Identification of impurities in technical metalaxyl.

作者信息

Dureja P, Tanwar R S, Choudhary P P

机构信息

Division of Agricultural Chemicals, Indian Agricultural Research Institute, New Delhi, India.

出版信息

Chemosphere. 2000 Nov;41(9):1407-10. doi: 10.1016/s0045-6535(99)00543-3.

DOI:10.1016/s0045-6535(99)00543-3

PMID:11057577

Abstract

Impurities such as 2,6-dimethylaniline, N-methyl-2,6-dimethylaniline, N-(1-methoxycarbonyl-ethyl)-2,6-dimethylaniline, N-methyl-N-(1-methoxycarbonyl-ethyl)-2,6-dimethylaniline, N-methyl-N-(1-methoxyacetyl)-2,6-dimethylaniline, N-(1-methoxyacetyl)-2,6-dimethylaniline and N-ethyl-N-(methoxyacetyl)-2,6-dimethylaniline present in samples of technical metalaxyl were isolated by column chromatography and identified by nuclear magnetic resonance, mass spectroscopy and comparison with reference compounds.

摘要

精甲霜灵原药样品中存在的杂质，如2,6-二甲基苯胺、N-甲基-2,6-二甲基苯胺、N-(1-甲氧羰基乙基)-2,6-二甲基苯胺、N-甲基-N-(1-甲氧羰基乙基)-2,6-二甲基苯胺、N-甲基-N-(1-甲氧基乙酰基)-2,6-二甲基苯胺、N-(1-甲氧基乙酰基)-2,6-二甲基苯胺和N-乙基-N-(甲氧基乙酰基)-2,6-二甲基苯胺，通过柱色谱法分离，并通过核磁共振、质谱以及与参考化合物比较进行鉴定。