Fronda G R, Resegotti A, Astegiano M, Farina E C, Patelli E, Giustetto A, De Paolis P
Dipartimento Medico Chirurgico, Azienda Ospedaliera S. Giovanni Battista, Torino.
Minerva Chir. 2000 Jun;55(6):431-5.
Only a part of patients suffering from Crohn's disease has enteric fistulae and a different behaviour of Crohn's disease with fistulae is reported in the literature. Aim of this paper is to evaluate if enteric fistulae are a factor conditioning mortality, morbidity and overall postoperative course, in patients with Crohn's disease.
Data on the postoperative course of 126 laparotomies for Crohn's disease, performed between November 1993 and July 1998, have been prospectively examined. Moreover, the presence of enteric fistula has been evaluated during surgery.
Out of 126 interventions, in 58 (46%) enteric fistulae were present. Mortality (5.2% vs 0), morbidity (14.5% vs 7.3%), necessity for a temporary ostomy (20.4% vs 3.5%) were greater in those patients with fistula, as compared as those without fistula.
In conclusion, it is suggested that Crohn's disease with fistulae is a different type of disease, with higher mortality and morbidity rates.
仅一部分克罗恩病患者有肠瘘，且文献报道有瘘的克罗恩病表现不同。本文旨在评估肠瘘是否为影响克罗恩病患者死亡率、发病率及术后总体病程的一个因素。
前瞻性研究了1993年11月至1998年7月间因克罗恩病行剖腹手术的126例患者的术后病程数据。此外，术中评估肠瘘的存在情况。
126例手术中，58例（46%）存在肠瘘。与无瘘患者相比，有瘘患者的死亡率（5.2%对0）、发病率（14.5%对7.3%）、行临时造口术的必要性（20.4%对3.5%）更高。
总之，提示有瘘的克罗恩病是一种不同类型的疾病，死亡率和发病率更高。
