Nistri R, Vitali A, Basili G, Carrieri P
U. O. Patologia Chirurgica II, Università degli Studi, Firenze.
Minerva Chir. 2000 Jun;55(6):451-3.
An ischemic origin of acute pancreatitis has been considered for a long time, at least as an aiding factor: ischemia has a fundamental role in the development of necrotizing pancreatitis from an oedematous one. Shock, heart condition and celiac-mesenteric ischemia can determine the onset of an acute pancreatitis through local ischemic lesions. Personal experience with a case of acute pancreatitis following an intestinal ischemic failure is reported. The duration of ischemia and, in particular, the free radicals formation during the organ reperfusion have been considered as the main pathogenetic factors. In the observed case, the ischemic hypothesis seems to be supported from the lack of other known factors and from the intestinal ischemic failure episode.
急性胰腺炎的缺血性起源长期以来一直被认为,至少是一个辅助因素:缺血在水肿性胰腺炎发展为坏死性胰腺炎过程中起关键作用。休克、心脏疾病和腹腔 - 肠系膜缺血可通过局部缺血性病变引发急性胰腺炎。本文报告了一例因肠道缺血性衰竭后发生急性胰腺炎的个人病例。缺血持续时间,尤其是器官再灌注期间自由基的形成,被认为是主要的发病因素。在观察到的病例中,缺血假说似乎得到了缺乏其他已知因素以及肠道缺血性衰竭事件的支持。