Girzu-Amblard M, Carnat A, Fraisse D, Carnat A P, Lamaison J L
Laboratoire de Pharmacognosie et Phytothérapie, Faculté de Pharmacie, 28, place Henri-Dunant, F 3000 Clermont-Ferrand. Manuscrit reçu le 14 novembre 1997.
Ann Pharm Fr. 2000 Oct;58(5):341-5.
Dried flowering tops of Hypericum perforatum L. (16 batches) and H. maculatum (3 batches) were studied according to the harvest period. The mean levels of the flavonoid and dianthranoid compounds were respectively: total flavonoids 3.20 and 3.92%, hyperoside 0.87 and 2. 12%, rutin 0.54 and 0.02%, isoquercitrin 0.48 and 0.75%; total dianthranoids 0.14 and 0.13%, hypericin 0.04 and 0.02%, pseudohypericin 0.08 and 0.11%. The flavonoid and dianthranoid levels were higher in young flowering tops of H. perforatum. 3 commercial batches were also examined for a comparative study. Pharmacopoeial specifications are proposed for a revision of the monograph "St.-John's-wort".
对贯叶连翘（16批）和斑点叶金丝桃（3批）的干燥花顶按采收期进行了研究。黄酮类和二蒽酮类化合物的平均含量分别为：总黄酮3.20%和3.92%，金丝桃苷0.87%和2.12%，芦丁0.54%和0.02%，异槲皮苷0.48%和0.75%；总二蒽酮0.14%和0.13%，金丝桃素0.04%和0.02%，假金丝桃素0.08%和0.11%。贯叶连翘幼嫩花顶中的黄酮类和二蒽酮类含量较高。还对3个商业批次进行了比较研究。建议修订“圣约翰草”专论的药典规格。
