人类染色体区域2q31→q32.1中两个脆性位点和七个同源异型盒基因的聚类。
Clustering of two fragile sites and seven homeobox genes in human chromosome region 2q31-->q32.1.
作者信息
Limongi M Z, Pelliccia F, Gaddini L, Rocchi A
机构信息
Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Roma, Italia.
出版信息
Cytogenet Cell Genet. 2000;90(1-2):151-3. doi: 10.1159/000015651.
PMID:11060466
Abstract
In this study we have used FISH to examine the relationship between a group of homeobox genes, namely DLX1/DLX2, EVX2 and four HOXD genes (10, 11, 12, 13), that map to region q31 on chromosome 2, and the FRA2G and FRA2H fragile sites located at 2q31 and 2q32.1 respectively. Our results indicate that these homeobox genes lie between the two fragile regions.
摘要
在本研究中，我们使用荧光原位杂交技术（FISH）来检测一组同源框基因（即DLX1/DLX2、EVX2和四个HOXD基因：10、11、12、13）之间的关系，这些基因定位于2号染色体的q31区域，以及分别位于2q31和2q32.1的FRA2G和FRA2H脆性位点。我们的结果表明，这些同源框基因位于两个脆性区域之间。
Zotero 插件