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[在一名患有喉癌和甲状旁腺腺瘤的患者中使用(99m)锝-甲氧基异丁基异腈单光子发射计算机断层显像(SPECT)]

[Use of SPECT with (99m)Tc-Sestamibi in a patient affected by laryngeal carcinoma and parathyroid adenoma].

作者信息

Giordano A, Galli J, Corina L, Samanes Gajate A M, D'Andrea G, Almadori G

机构信息

Servicio de Medicina Nuclear, Università Cattolica del Sacro Cuore, Roma.

出版信息

Rev Esp Med Nucl. 2000 Jun;19(3):211-4.

Abstract

We report the case of a patient with a laryngeal carcinoma in whom asymptomatic hyperparathyroidism was also detected during the preoperative work-up. A planar (201)Thallium/(99m)Tc-pertecnetate subtraction scintigraphy was performed in order to locate the suspected parathyroid adenoma. The study showed a single area of increased (201)Thallium uptake just above the thyroid isthmus, likely due to the laryngeal tumor. The scintigraphic study was repeated using (99m)Tc-Sestamibi and (99m)Tc-pertechnetate and employing the SPECT technique. Both SPECT studies made it possible to identify correctly the parathyroid adenoma, located inferiorly and in a posterior position to the lower third of the right thyroid lobe. The laryngeal tumor and parathyroid adenoma could be excised in a single surgery session. This case is of interest due to the rarity of the coexistence of two neck tumors and the clear advantage shown by the SPECT technique with (99m)Tc-Sestamibi over the planar technique with 201Thallium.

摘要

我们报告了一例喉癌患者,在术前检查中还发现了无症状性甲状旁腺功能亢进。为了定位疑似甲状旁腺腺瘤,进行了平面(201)铊/(99m)锝-高锝酸盐减影闪烁扫描。研究显示,甲状腺峡部上方有一个单一的(201)铊摄取增加区域,可能是由于喉部肿瘤所致。使用(99m)锝-甲氧基异丁基异腈和(99m)锝-高锝酸盐并采用SPECT技术重复进行闪烁扫描研究。两项SPECT研究均能正确识别位于右甲状腺叶下三分之一下方且偏后的甲状旁腺腺瘤。喉肿瘤和甲状旁腺腺瘤可在一次手术中切除。由于两种颈部肿瘤并存的情况罕见,且(99m)锝-甲氧基异丁基异腈的SPECT技术相对于(201)铊平面技术具有明显优势,因此该病例具有一定的研究价值。

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