Ollikainen J
Department of Pediatrics, Kuopio University Hospital, Kuopio, Finland.
Pediatr Pulmonol. 2000 Nov;30(5):402-5. doi: 10.1002/1099-0496(200011)30:5<402::aid-ppul6>3.0.co;2-j.
To explore the association of perinatal Ureaplasma urealyticum infection and the need for hospital care during infancy, a cohort of preterm infants were prospectively followed for 12 months. Perinatal U. urealyticum infection was defined as the presence of U. urealyticum in the samples obtained from the trachea and blood. During the first year of life, the infants of the study cohort required 73 hospital admissions resulting in 734 hospital days. The 22 infants with perinatal U. urealyticum infection needed more hospital days for therapy than the 18 infants without infection (546 vs. 188 days, P = 0.042). The difference was caused by an increase in respiratory tract diseases among children with perinatal U. urealyticum infection. Chronic lung disease caused more admissions in infants with perinatal U. Urealyticum infection than without it (P = 0.035). The results indicate that perinatal U. urealyticum infection affects the health of premature infants far beyond the perinatal period.
为探讨围产期解脲脲原体感染与婴儿期住院需求之间的关联，对一组早产儿进行了为期12个月的前瞻性随访。围产期解脲脲原体感染定义为从气管和血液样本中检测到解脲脲原体。在生命的第一年，研究队列中的婴儿需要73次住院治疗，累计住院天数达734天。22例围产期解脲脲原体感染的婴儿比18例未感染的婴儿需要更多的住院天数进行治疗（546天对188天，P = 0.042）。这种差异是由于围产期解脲脲原体感染儿童呼吸道疾病增加所致。慢性肺病导致围产期解脲脲原体感染婴儿的住院次数多于未感染婴儿（P = 0.035）。结果表明，围产期解脲脲原体感染对早产儿健康的影响远远超出围产期。
