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[干扰CRP检测的因素(从制造商角度)]

[Factors interfering with CRP assay (from the manufacturer's perspective)].

作者信息

Tomiyama R

机构信息

Development Department, Iatron Laboratories, INC., Tokyo.

出版信息

Rinsho Byori. 2000 Aug;48(8):760-3.

PMID:11064601
Abstract

Recently, there have been many highly sensitive methods for CRP assay. However, there are also many factors that interfere with CRP assay. We are taking measures to avoid interference due to factors such as, myeloma protein, rheumatoid factor, lipaemia(a substance similar to detergent in the capillary tube, etc). Currently CRP assay methods which are not influenced by these factors are available. However, other unknown factors that interfere with CRP assay have become apparent. We think that these are peculiar to the immunoassay. We are taking measures to identify these interference factors and resolve the problem. In the following, we will explain some experiments that will protect our re-agent from these interference factors.

摘要

最近,出现了许多用于检测CRP的高灵敏度方法。然而,也有许多因素会干扰CRP检测。我们正在采取措施避免因骨髓瘤蛋白、类风湿因子、脂血(毛细管中类似洗涤剂的物质等)等因素造成的干扰。目前有不受这些因素影响的CRP检测方法。然而,其他干扰CRP检测的未知因素已变得明显。我们认为这些因素是免疫测定所特有的。我们正在采取措施识别这些干扰因素并解决该问题。在下文中,我们将解释一些能使我们的试剂免受这些干扰因素影响的实验。

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