Hoshino N, Murata T, Oka K, Kawakami K, Hoshino K, Sekoguchi S, Suga T, Nishimura A, Kato M, Hamada M
Department of Internal Mecidine, JA Suzuka Hospital, Mie.
Intern Med. 2000 Nov;39(11):914-9. doi: 10.2169/internalmedicine.39.914.
We report two patients with gastrointestinal stromal tumors (GISTs) of the small intestine that expressed c-kit protein (CD117). One was a 68-year-old woman with epigastralgia and vomiting. A submucosal tumor of the upper jejunum was detected, and partial resection was carried out. The histology revealed a GIST negative for CD34 but positive for CD117. The other was a 42-year-old woman with progressive anemia, melena and lower abdominal pain. Intussusception was detected, and a partial resection was carried out. A submucosal tumor of the lower jejunum was noted. The histology revealed a GIST positive for both CD34 and CD117.
我们报告了两名患有小肠胃肠道间质瘤（GIST）且表达c-kit蛋白（CD117）的患者。其中一名是68岁女性，有上腹部疼痛和呕吐症状。检测到空肠上段有一个黏膜下肿瘤，并进行了部分切除。组织学检查显示该GIST对CD34呈阴性，但对CD117呈阳性。另一名是42岁女性，有进行性贫血、黑便和下腹部疼痛。检测到肠套叠，并进行了部分切除。发现空肠下段有一个黏膜下肿瘤。组织学检查显示该GIST对CD34和CD117均呈阳性。
