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Br J Exp Pathol. 1975 Apr;56(2):119-23.
Coxsackievirus B3 causes foetal wastage and growth retardation in mice which may be attributed to the action of the virus in destroying the maternal exocrine pancreas. Injection of virus on Day 4 or 8 of gestation caused greater foetal wastage than injection at 12 days. Foetal and placental weights in infected animals were less than in the controls but did not vary according to the time of infection. Little support is offered for the view that the mouse foetus differs in its susceptibility to Coxsackievirus B3 according to the stage in gestation of infection.
柯萨奇病毒B3可导致小鼠出现胚胎死亡和生长发育迟缓，这可能归因于该病毒破坏母体胰腺外分泌部的作用。在妊娠第4天或第8天注射病毒比在第12天注射导致更多的胚胎死亡。感染动物的胎儿和胎盘重量低于对照组，但并不随感染时间而变化。关于小鼠胎儿对柯萨奇病毒B3的易感性因感染时的妊娠阶段而异这一观点，几乎没有证据支持。
