Tomobe M, Miyanaga N, Kawai K, Kikuchi K, Uchida K, Takeshima H, Hasegawa Y, Nagasawa T, Akaza H
Department of Urology, University of Tsukuba.
Nihon Hinyokika Gakkai Zasshi. 2000 Sep;91(9):618-22. doi: 10.5980/jpnjurol1989.91.618.
We reviewed cases of intrascrotal tumors treated at our institution except for germ cell testicular tumors.
From 1977 to 1998 (22 years), 120 cases of intrascrotal tumors treated at the University of Tsukuba. Of these, 15 cases (12.5%) were not germ cell testicular tumors. The patients' ages varied between 2 and 77 years with a mean of 49.6.
The most common complaint regarding symptoms was painless testicular enlargement. Tumor weight ranged from 2 to 200 g, with an average of 104.6 g. The histological diagnoses of 15 patients were 8 malignant lymphomas, 2 paratesticular rhabdomyosarcomas, 2 metastatic tumors (origin; stomach and prostate), 1 epidermoid cyst, 1 cyst of tunica testis, and 1 adenomatoid tumor. As for the cases with malignant lymphoma, all of them were non-Hodgkin's lymphoma whose clinical stages were stage I in 2 cases and stage IV in 6 cases. Five 8 patients died in spite of systemic chemotherapy after an orchiectomy, whereas 2 cases with metastatic tumors died of primary cancer, and two cases with paratesticular rhabdomyosarcoma are still alive and have had no evidence of disease.
Intrascrotal tumors except for germ cell testicular tumors are not common, and consist of various diseases. In particular, some kinds of malignant lymphoma mimic anaplastic seminoma histopathologically. Therefore, accurate diagnosis and precise treatment is important in the patient with intrascrotal tumors.
我们回顾了在本机构接受治疗的阴囊内肿瘤病例,但不包括生殖细胞睾丸肿瘤。
1977年至1998年(共22年),筑波大学共治疗了120例阴囊内肿瘤患者。其中,15例(12.5%)并非生殖细胞睾丸肿瘤。患者年龄在2岁至77岁之间,平均年龄为49.6岁。
最常见的症状主诉是无痛性睾丸肿大。肿瘤重量在2克至200克之间,平均为104.6克。15例患者的组织学诊断结果为:8例恶性淋巴瘤、2例睾丸旁横纹肌肉瘤、2例转移性肿瘤(原发部位;胃和前列腺)、1例表皮样囊肿、1例睾丸鞘膜囊肿和1例腺瘤样肿瘤。对于恶性淋巴瘤病例,所有均为非霍奇金淋巴瘤,其中2例临床分期为I期,6例为IV期。8例患者中有5例在睾丸切除术后尽管接受了全身化疗仍死亡,而2例转移性肿瘤患者死于原发癌症,2例睾丸旁横纹肌肉瘤患者仍然存活且无疾病证据。
除生殖细胞睾丸肿瘤外,阴囊内肿瘤并不常见,且由多种疾病组成。特别是,某些类型的恶性淋巴瘤在组织病理学上类似于间变性精原细胞瘤。因此,对于阴囊内肿瘤患者,准确诊断和精确治疗非常重要。