Muscardin L M, Bellocci M, Balus L
Istituto San Gallicano, IRCCS, Via San Gallicano 25/a, Rome, Italy.
Br J Dermatol. 2000 Oct;143(4):884-7. doi: 10.1046/j.1365-2133.2000.03798.x.
We report a case of adult colloid milium in a 47-year-old mechanic with a long history of professional contact with lubricating oils and of sun exposure. In addition to the typical translucent papules seen on the forehead, there were warty papules on the backs of both hands with unusual histological and ultrastructural features: marked hyperplasia of the epidermis with orthokeratotic hyperkeratosis and papillary deposits of colloid material that were contiguous with the basal layer of the epidermis. The hand lesions caused by occupational exposure to mineral oils and solar radiation represent an occupational variant of adult colloid milium.
我们报告了一例47岁机械师的成人胶样粟丘疹病例，该患者有长期职业接触润滑油及日晒史。除了前额出现典型的半透明丘疹外，双手背部还有疣状丘疹，具有不寻常的组织学和超微结构特征：表皮显著增生伴正角化过度，以及与表皮基底层相邻的胶样物质乳头层沉积。职业性接触矿物油和太阳辐射导致的手部病变代表了成人胶样粟丘疹的一种职业变体。
