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一种口服缓释硝苯地平片(拜新同控释片)及其在双重对比钡灌肠检查中的表现。

An oral modified-release nifedipine tablet (Adalat LA) and its appearance on double contrast barium enema.

作者信息

Bleehen R E

机构信息

Department of Diagnostic Radiology, University Hospital of Wales, Heath Park, Cardiff, UK.

出版信息

Clin Radiol. 2000 Nov;55(11):837-8. doi: 10.1053/crad.2000.0544.

DOI:10.1053/crad.2000.0544
PMID:11069738
Abstract

Adalat LA 30 mg and 60 mg tablets are widely prescribed oral modified release nifedipine preparations with a porous, non-digestible plastic tablet coating which is required in order to effect the osmotically driven slow release mechanism. These tablets may therefore be seen anywhere along the gastrointestinal tract and are passed apparently whole in the faeces. An example of the appearance within the rectum of Adalat LA 30 (Bayer) on double contrast barium enema is shown and the main features described. A review of the literature is given. Recognition of the appearances during the barium enema examination will prompt those performing the procedure to question the drug history where relevant and will reduce the incidence of false- positive reporting.Bleehen, R. E. (2000). Clinical Radiology55, 837-838.

摘要

拜新同控释片30毫克和60毫克片剂是广泛应用的口服硝苯地平控释制剂,其具有多孔、不可消化的塑料片包衣,以实现渗透驱动的缓释机制。因此,这些片剂可能在胃肠道的任何部位被发现,并显然完整地随粪便排出。展示了双对比钡灌肠时拜新同控释片30(拜耳公司)在直肠内的外观示例并描述了主要特征。同时给出了文献综述。在钡灌肠检查中识别出这些表现将促使进行该检查的人员在相关情况下询问用药史,并减少假阳性报告的发生率。布莱亨,R.E.(2000年)。《临床放射学》55卷,第837 - 838页。

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