Sietzen W, Kienitz M, Knothe H
Dtsch Med Wochenschr. 1975 Dec 26;100(52):2636-41. doi: 10.1055/s-0028-1106599.
Within 4 years 1400 children were investigated for urinary-tract infection in a long-term study. Children with manifest infection were treated and followed-up. In 59 children with chronic pyelonephritis 159 recurrences were observed: 146 were reinfections (change of organism) and 13 relapses (organism unchanged). Serotyping of 0-antigens showed differences between children with chronic pyelonephritis and children with a single exacerbation within the observation period. Reinfection with resistant bacteria mainly occurred shortly after cessation of therapy.
在一项长期研究中,4年内对1400名儿童进行了尿路感染调查。对有明显感染的儿童进行了治疗和随访。在59例慢性肾盂肾炎患儿中,观察到159次复发:146次为再感染(病原体改变),13次为复发(病原体未改变)。0抗原血清分型显示,慢性肾盂肾炎患儿与观察期内单次病情加重的患儿之间存在差异。耐药菌再感染主要发生在治疗停止后不久。