Bieniaszewska M, Balon J, Hellmann A
Kliniki Hematologii Instytutu Chorób Wewnetrznych AM w Gdańsku.
Pol Merkur Lekarski. 2000 Jul;8(49):479-80.
A case of severe headache in a young woman is described. The headache was not associated with additional neurological findings. In peripheral blood extremely high count of platelets was found. Additional examinations supported the diagnosis of essential thrombocythemia (ET). As a first line treatment thrombocytapheresis was performed. The introduced hydroxyurea treatment was complicated with dysmenorrhea and neutropenia. It was the reason to the use anagrelide--a new antiplatelet drug--in the therapy of ET. The treatment with anagrelide was free of previously mentioned complications. After one year of observation the platelet count was still effectively reduced.
描述了一名年轻女性严重头痛的病例。该头痛与其他神经系统检查结果无关。在外周血中发现血小板计数极高。进一步检查支持原发性血小板增多症（ET）的诊断。作为一线治疗，进行了血小板单采术。引入的羟基脲治疗出现痛经和中性粒细胞减少的并发症。这就是在ET治疗中使用阿那格雷——一种新型抗血小板药物——的原因。阿那格雷治疗未出现上述并发症。经过一年的观察，血小板计数仍有效降低。
