Takayama H, Mihara B, Kobayashi M, Hozumi A, Sadanaga H, Gomi S
Mihara Memorial Hospital, Gunma, Japan.
No To Shinkei. 2000 Oct;52(10):919-23.
Diffusion-weighted imaging(DWI) has been demonstrated to be valuable for assessment of ischemic stroke patients. The aim of this study is to evaluate clinical usefulness of DWI in the diagnosis of transient ischemic attack(TIA). Nineteen patients with symptoms of TIA were studied. DWI was taken with 1.5 Tesla MRI system using spin echo EPI sequence. Seven patients revealed areas of hyperintensity (brightness) on DWI and of hypointensity on apparent diffusion coefficient(ADC) maps relative to normal brain. As the duration of TIA symptom elongated, the percentage of patients with DWI abnormalities became higher. DWI enabled to detect areas of hyperintense lesion in all three patients as early as 3 hours after the onset, while conventional T2 weighted imaging showed in one. All the DWI abnormalities were irreversible in spite of the complete recovery from TIA. DWI is an useful technique for the detection of responsible lesions in TIA. However, TIA cannot be ruled out even if DWI does not demonstrate any abnormal signals.
弥散加权成像(DWI)已被证明对评估缺血性中风患者具有重要价值。本研究的目的是评估DWI在短暂性脑缺血发作(TIA)诊断中的临床实用性。对19例有TIA症状的患者进行了研究。使用自旋回波EPI序列,通过1.5特斯拉MRI系统进行DWI检查。7例患者在DWI上显示相对于正常脑的高信号(明亮)区域,在表观扩散系数(ADC)图上显示低信号区域。随着TIA症状持续时间延长,DWI异常患者的百分比升高。DWI能够在发病后3小时内最早在所有3例患者中检测到高信号病变区域,而传统T2加权成像仅在1例中显示。尽管TIA已完全恢复,但所有DWI异常均不可逆。DWI是检测TIA责任病灶的有用技术。然而,即使DWI未显示任何异常信号,也不能排除TIA。