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[不可手术切除的恶性胆管梗阻的姑息性内镜支架引流术]

[Palliative endoscopic stent drainage of non-operable malignant biliary obstruction].

作者信息

Kleveland P M, Fougner R

机构信息

Medisinsk avdeling, Regionsykehuset i Trondheim.

出版信息

Tidsskr Nor Laegeforen. 2000 Sep 10;120(21):2513-6.

Abstract

BACKGROUND

Endoscopic stenting is the treatment of choice for inoperable malignant biliary obstruction. The standard plastic stents in use, however, tend to clog with time.

MATERIAL AND METHODS

We report the patient survival and stent patency rates in two separate groups of patients treated endoscopically for malignant biliary strictures on the basis of a retrospective review of patient medical records. The first group of 27 patients was treated with small caliber polyethylene stents in 1997. The second group of ten selected patients with fairly good life expectancy was treated with self-expandable wallstents due to early plastic stent occlusion in 1998.

RESULTS

The median stent patency and patient survival of patients treated with plastic stents was 11 and 14 weeks, respectively. Early stent occlusion occurred in seven patients. The median stent patency and patient survival of the patients treated with wallstents were 25 and 32 weeks, respectively. Late stent occlusion due to tumour ingrowth occurred in two patients.

INTERPRETATION

The last generation of self-expandable wallstent is endoscopically easy to insert and represents a valuable supplement to standard plastic stenting. Due to high cost, however, metal stents should preferably be offered patients with early plastic stent occlusion and estimated good life expectancy.

摘要

背景

内镜支架置入术是无法手术切除的恶性胆管梗阻的首选治疗方法。然而,目前使用的标准塑料支架往往会随着时间的推移而堵塞。

材料与方法

我们通过回顾患者病历,报告了两组分别接受内镜治疗恶性胆管狭窄患者的生存情况和支架通畅率。第一组27例患者于1997年接受小口径聚乙烯支架治疗。第二组10例预期寿命相当长的患者因1998年早期塑料支架堵塞而接受自膨式Wallstent支架治疗。

结果

接受塑料支架治疗的患者支架通畅时间中位数和患者生存时间中位数分别为11周和14周。7例患者发生早期支架堵塞。接受Wallstent支架治疗的患者支架通畅时间中位数和患者生存时间中位数分别为25周和32周。2例患者因肿瘤长入发生晚期支架堵塞。

解读

最新一代自膨式Wallstent支架在内镜下易于置入,是标准塑料支架置入术的一种有价值的补充。然而,由于成本高昂,金属支架最好提供给早期塑料支架堵塞且预期寿命良好的患者。

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