Raine P A, Young D G
Dev Med Child Neurol Suppl. 1975(35):111-6. doi: 10.1111/j.1469-8749.1975.tb03589.x.
A study was made of the pattern of bacterial colonisation during the first month of life in a group of 116 newborn infants with spina bifida. 55 patients subsequently developed a total of 90 infective episodes and in over three-quarters of these episodes there was a correlation between the infecting and colonising organisms. The principal sites of infection were the lesion, the ventricles and the urinary tract, and infection accounted for 27 of the 35 deaths in the series. Some of the factors governing the pattern of colonisation and the development of infection in newborn patients are discussed.
对116名患有脊柱裂的新生儿出生后第一个月的细菌定植模式进行了研究。55名患者随后共发生了90次感染发作，在超过四分之三的这些发作中，感染菌和定植菌之间存在相关性。主要感染部位是病变部位、脑室和泌尿道，感染占该系列35例死亡中的27例。讨论了一些影响新生儿患者定植模式和感染发生的因素。
