Chan P W, Goh A Y, Lum L C
Department of Paediatrics, University Malaya Medical Centre, Kuala Lumpur.
Med J Malaysia. 1999 Dec;54(4):487-91.
Severe bronchiolitis requiring mechanical ventilation is uncommon and is associated with the risk of barotrauma. We report our experience with 25 (42%) of 60 infants admitted to the Paediatric Intensive Care Unit (PICU) with severe bronchiolitis who required mechanical ventilation. Eighteen patients (72%) had severe hypoxaemia (PaO2/FiO2 < 250). The mean airway pressure required ranged from 5.8 to 15.6 cmH2O with median ventilation duration of 4.0 days (range 2.0-14.0 days). Oxygenation improved significantly within 12 hours of intubation. There was only one death. Mechanical ventilation is required in a subset of patients for severe bronchiolitis and is effective and generally well tolerated.
需要机械通气的重症细支气管炎并不常见，且伴有气压伤风险。我们报告了60例因重症细支气管炎入住儿科重症监护病房（PICU）并需要机械通气的婴儿中25例（42%）的治疗经验。18例患者（72%）存在严重低氧血症（动脉血氧分压/吸入氧分数值<250）。所需平均气道压力范围为5.8至15.6厘米水柱，中位通气时间为4.0天（范围2.0 - 14.0天）。插管后12小时内氧合情况显著改善。仅1例死亡。重症细支气管炎患者中的一部分需要机械通气，且该方法有效且通常耐受性良好。
