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法国一家综合医院中出现了对糖肽类药物敏感性降低的金黄色葡萄球菌菌株的暴发。

An outbreak of Staphylococcus aureus strains with reduced susceptibility to glycopeptides in a French general hospital.

作者信息

Pina P, Marliere C, Vandenesch F, Bedos J P, Etienne J, Allouch P Y

机构信息

Centre Hospitalier de Versailles, Le Chesnay, France.

出版信息

Clin Infect Dis. 2000 Nov;31(5):1306-8. doi: 10.1086/317464.

DOI:10.1086/317464
PMID:11073773
Abstract

We describe the isolation of Staphylococcus aureus isolates with glycopeptide heteroresistant subpopulation from 15 patients (11 with colonizations and 4 with infections) in a French hospital. Non of the patients were previously treated with glycopeptides. The 15 isolates belonged to 2 different pulsotypes unrelated to other methicillin-resistant S. aureus isolates from the same hospital.

摘要

我们描述了在一家法国医院中,从15名患者(11名定植患者和4名感染患者)中分离出具有糖肽异质性耐药亚群的金黄色葡萄球菌菌株。这些患者之前均未接受过糖肽类药物治疗。这15株菌株属于2种不同的脉冲型,与来自同一家医院的其他耐甲氧西林金黄色葡萄球菌菌株无关。

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An outbreak of Staphylococcus aureus strains with reduced susceptibility to glycopeptides in a French general hospital.法国一家综合医院中出现了对糖肽类药物敏感性降低的金黄色葡萄球菌菌株的暴发。
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引用本文的文献

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Daptomycin Resistance in Clinical MRSA Strains Is Associated with a High Biological Fitness Cost.临床耐甲氧西林金黄色葡萄球菌(MRSA)菌株对达托霉素的耐药性与较高的生物学适应性代价相关。
Front Microbiol. 2017 Dec 5;8:2303. doi: 10.3389/fmicb.2017.02303. eCollection 2017.
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Reduced vancomycin susceptibility in Staphylococcus aureus, including vancomycin-intermediate and heterogeneous vancomycin-intermediate strains: resistance mechanisms, laboratory detection, and clinical implications.金黄色葡萄球菌中万古霉素敏感性降低,包括万古霉素中介和异质性万古霉素中介菌株:耐药机制、实验室检测及临床意义。
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First report of vancomycin-resistant staphylococci isolated from healthy carriers in Brazil.
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New developments in antibacterial choice for lower respiratory tract infections in elderly patients.老年患者下呼吸道感染抗菌药物选择的新进展
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