Plant J, Glynn A A
J Infect Dis. 1976 Jan;133(1):72-8. doi: 10.1093/infdis/133.1.72.
Eight strains of inbred mice fell into two sharply defined groups. Four strains (CBA, A/JAX, C3H/He, and DBA/2) were resistant (LD50, greater than 10(5)) to Salmonella typhimurium C5 given subcutaneously. The other four strains (Balb/c, C57BL, B10.D2 [new line], and DBA/1) were susceptible (LD50, less than 10). No intermediate resistance was seen. Examination of the F1, F2, and parental backcross generations bred from matings of CBA and Balb/c mice showed that resistance behaved as a simple Mendelian dominant. Resistance was not linked to H-2 genes, and no useful marker has yet been found. However, as previously demonstrated in the parent strains, resistance in the hybrids was related to the ability to produce a good delayed-type hypersensitivity reaction to an extract of S. typhimurium.
八个近交系小鼠品系分为两个界限分明的组。四个品系（CBA、A/JAX、C3H/He和DBA/2）对皮下注射的鼠伤寒沙门氏菌C5有抗性（半数致死量，大于10⁵）。另外四个品系（Balb/c、C57BL、B10.D2[新系]和DBA/1）易感（半数致死量，小于10）。未观察到中间抗性。对CBA和Balb/c小鼠交配产生的F1、F2及亲本回交世代的检测表明，抗性表现为简单的孟德尔显性。抗性与H-2基因不连锁，且尚未发现有用的标记。然而，如亲本品系中先前所示，杂种中的抗性与对鼠伤寒沙门氏菌提取物产生良好迟发型超敏反应的能力有关。
