Layfield L J, Gopez E V
Department of Pathology, University of Utah, Salt Lake City, Utah 84132, USA.
Diagn Cytopathol. 2000 Dec;23(6):409-13. doi: 10.1002/1097-0339(200012)23:6<409::aid-dc10>3.0.co;2-5.
A case of insular carcinoma of the thyroid is presented, in which a prominence of microfollicular structures resulted in difficulty in distinguishing it from a follicular neoplasm of the thyroid. The patient presented with a single discrete thyroid nodule, aspiration of which yielded markedly cellular smears containing cells lying singly, in tight clusters and microfollicles. Criteria for separation of insular carcinoma of the thyroid from follicular neoplasms include the presence of intact insulae, high cellularity, and the presence of small amounts of necrotic debris.
本文报告一例甲状腺岛状癌，其中微滤泡结构突出，难以与甲状腺滤泡性肿瘤相鉴别。患者表现为单个孤立的甲状腺结节，细针穿刺涂片显示细胞明显增多，细胞呈单个、紧密聚集及微滤泡状排列。甲状腺岛状癌与滤泡性肿瘤鉴别的标准包括完整岛状结构的存在、高细胞密度以及少量坏死碎片的存在。
