Sinclair M C, LeBoutillier M, Gee W, Phillips T, Singer R L
Department of Surgery, Lehigh Valley Hospital, Allentown, PA 18105-1556, USA.
Heart Surg Forum. 2000;3(2):127-32; discussion 132-3.
Eighteen patients with unstable angina underwent repeat myocardial revascularization without cardiopulmonary bypass using saphenous vein grafts from either the left (13) or right (2) axillary arteries or the descending thoracic aorta (3). Patients' ages ranged from 53 to 85 years. Left ventricular ejection fractions ranged from 15% to 60%.
In 14 patients, the heart was exposed through an anterior thoracotomy, a minimally invasive direct coronary artery bypass (MIDCAB) technique. In 3 patients a left posterolateral thoractomy (lateral MIDCAB) was performed. One patient underwent repeat sternotomy (off-pump coronary artery bypass: OPCAB). In MIDCAB and lateral MIDCAB patients, the "target" vessel was a coronary artery in 8 patients and a previously placed vein graft in the remaining 9 patients. One patient underwent repeat sternotomy, and 3 coronary arteries were bypassed with a complex vein graft attached to the left axillary artery. Two patients died of mesenteric ischemia on the 2nd and 7th postoperative day. The remainder of patients were discharged from the hospital free of angina. Early graft patency was demonstrated by noninvasive vascular laboratory testing and/or angiography in the 13 survivors in whom the axillary artery had been the site of the proximal anastomosis.
Follow-up ranged from 1 to 25 months. No other patients have died, and none have undergone additional surgical or catheter-based procedures. Three patients have developed recurrent angina, and in 4 patients the extra-anatomic bypass grafts have apparently become occluded.
Extra-anatomic, off-pump bypass from the axillary artery or descending thoracic aorta to one or more coronary arteries can be performed safely in seriously ill patients requiring a repeat bypass procedure. The early results, regarding relief of angina, are encouraging.
18例不稳定型心绞痛患者接受了非体外循环下的再次心肌血运重建术,采用来自左腋动脉(13例)、右腋动脉(2例)或胸降主动脉(3例)的大隐静脉移植血管。患者年龄在53至85岁之间。左心室射血分数在15%至60%之间。
14例患者通过前外侧开胸术暴露心脏,采用微创直接冠状动脉旁路移植术(MIDCAB)技术。3例患者行左后外侧开胸术(外侧MIDCAB)。1例患者接受再次胸骨切开术(非体外循环冠状动脉旁路移植术:OPCAB)。在MIDCAB和外侧MIDCAB患者中,8例患者的“目标”血管为冠状动脉,其余9例患者的“目标”血管为先前植入的静脉移植血管。1例患者接受再次胸骨切开术,用连接至左腋动脉的复杂静脉移植血管绕过3条冠状动脉。2例患者分别在术后第2天和第7天死于肠系膜缺血。其余患者出院时无心绞痛症状。13例幸存者中,腋动脉为近端吻合部位,通过无创血管实验室检查和/或血管造影证实早期移植血管通畅。
随访时间为1至25个月。无其他患者死亡,也无患者接受额外的手术或导管介入治疗。3例患者出现复发性心绞痛,4例患者的解剖外旁路移植血管明显闭塞。
对于需要再次旁路手术的重症患者,可安全地进行从腋动脉或胸降主动脉到一条或多条冠状动脉的解剖外非体外循环旁路手术。在缓解心绞痛方面,早期结果令人鼓舞。