引言。慢性伤口愈合：当今及未来的技术解决方案。

Introduction. Healing chronic wounds: technologic solutions for today and tomorrow.

出版信息

Adv Skin Wound Care. 2000 May-Jun;13(2 Suppl):4-5.

Abstract

Wound repair is a highly orchestrated, integrated cellular and biochemical response to injury. The process includes coagulation, inflammation, proliferation, and remodeling. Each component involves a distinct but overlapping set of different cell types with different functions that migrate into the wound site in an orderly fashion. Certain pathophysiologic and metabolic conditions can alter this normal course of events so that healing is impaired or delayed, resulting in nonhealing wounds. Progress has been made in understanding the complex cellular and biochemical processes of the wound healing response, and technologic advances have allowed for new therapies to be developed to effectively treat these wounds.

摘要

伤口修复是对损伤的一种高度协调、综合的细胞和生化反应。该过程包括凝血、炎症、增殖和重塑。每个组成部分都涉及一组不同但相互重叠的具有不同功能的细胞类型，它们以有序的方式迁移到伤口部位。某些病理生理和代谢状况会改变这一正常的事件进程，从而导致愈合受损或延迟，形成不愈合伤口。在理解伤口愈合反应的复杂细胞和生化过程方面已取得进展，技术进步使得能够开发出新的疗法来有效治疗这些伤口。