Kühn C, Vente C, Dörner J, Ratayski H, Burchardi H
Zentrum Anästhesiologie, Rettungs- und Intensivmedizin, Universität Göttingen.
Anaesthesist. 2000 Sep;49(9):829-33. doi: 10.1007/s001010070056.
Pyoderma gangrenosum (PG) is a necrotizing and ulcerative skin disease of unknown cause. The pathogenesis is thought to be related to a defective immune response. The ulcerations appear spontaneously or after skin trauma. Development in a surgical wound can be misinterpreted as wound infection. However, in contrast to postoperative infections, treatment of PG requires immunosuppressive therapy. We report a case of PG following hip-joint surgery that was complicated by a severe life-threatening systemic inflammatory response syndrome (SIRS). Typically, wound and blood cultures were negative for pathogens. Prednisolone stopped the activity of the disease promptly.
坏疽性脓皮病（PG）是一种病因不明的坏死性溃疡性皮肤病。其发病机制被认为与免疫反应缺陷有关。溃疡可自发出现或在皮肤创伤后出现。手术伤口处发生坏疽性脓皮病可能会被误诊为伤口感染。然而，与术后感染不同，PG的治疗需要免疫抑制疗法。我们报告一例髋关节手术后发生的PG病例，该病例并发了严重的、危及生命的全身炎症反应综合征（SIRS）。通常情况下，伤口和血液培养均未发现病原体。泼尼松龙迅速抑制了疾病的进展。
