Schmidt G B, Bombeck C T, Bennett E J, Kotb K M
Langenbecks Arch Chir. 1975;Suppl:439-42. doi: 10.1007/978-3-662-05557-1_93.
Alternate patients believed to be at risk for developing ARDS were placed on CPAP for the first twenty-four hours post upper abdominal surgery. Ten of the 58 controls developed ARDS, requiring prolonged mechanical ventilation with a 30% mortality rate. Only one of the 59 CPAP patients developed evidence of ARDS. This patient, however, is believed to have had fluid overload, and responded quickly to diuretics and was extubated within two days. Thus, prophylactic CPAP has greatly decreased our postoperative morbidity and mortality related to respiratory causes.
对于被认为有发生急性呼吸窘迫综合征（ARDS）风险的择期患者，在上腹部手术后的头24小时给予持续气道正压通气（CPAP）治疗。58例对照组患者中有10例发生ARDS，需要长时间机械通气，死亡率为30%。59例接受CPAP治疗的患者中只有1例出现ARDS迹象。然而，该患者被认为存在液体超负荷，对利尿剂反应迅速，两天内就拔除了气管插管。因此，预防性使用CPAP已大大降低了我们术后与呼吸相关的发病率和死亡率。
