Schadewaldt H
Langenbecks Arch Chir. 1975 Nov;339:573-85. doi: 10.1007/BF01257562.
The introduction of antisepsis and asepsis brought about decisive changes in the dressing of wounds. For thousands of years, dressing material had been regarded as protection for wounds, absorbent material, or a base for healing substances, while healing per secundam intentionem by the production of "pus laudabile" was the general rule. With the advent of antisepsis, dressings became a type of medication, healing the wounds per primam intentionem. Different materials have been used over the years, but the most important steps in the development of new dressings were made in the nineteenth century, with the introduction of a degreased cotton and of medicated plasters.
防腐和无菌技术的引入给伤口包扎带来了决定性的变化。数千年来，敷料一直被视为伤口的保护物、吸收材料或愈合物质的载体，而通过产生“良性脓液”进行二期愈合是普遍的规则。随着防腐技术的出现，敷料成为了一种药物，可实现一期伤口愈合。多年来人们使用了不同的材料，但新型敷料发展中最重要的阶段是在19世纪，脱脂棉和药用膏药的引入。
