Mercado M A, Orozco H, Guillén-Navarro E, Acosta E, López-Martínez L M, Hinojosa C, Hernández J, Tielve M
Department of Surgery, Instituto Nacional de la Nutrición Salvador Zubirán, Mexico City, Mexico.
J Gastrointest Surg. 2000 Sep-Oct;4(5):453-7. doi: 10.1016/s1091-255x(00)80085-2.
The use of small-diameter portosystemic shunts for the treatment of bleeding esophageal varices caused by portal hypertension has emerged as an outgrowth of the development of polytetrafluoroethylene vascular grafts, which allow the use of a narrow lumen. We report our experience with this type of graft over a 10-year period. Thirty-three patients with good liver function (Child-Pugh class A) were electively operated. The average age of these patients was 45 years (range 17 to 71 years). Twenty-nine patients had liver cirrhosis, one had portal fibrosis, and three had idiopathic portal hypertension. Operative mortality was 3%, and the rebleeding rate was 15%. Postoperative encephalopathy was observed in 14 patients (11%), three of whom had grade III to IV encephalopathy. The remaining 11 patients, had mild encephalopathy that was easily controlled. Postoperative angiography showed shunt patency in 81% of the patients, reduction in portal vein diameter in 33% of the patients, and portal vein thrombosis in 6%. Good postoperative quality of life was observed in 63% of the patients. Survival according to the Kaplan-Meier actuarial method was 81% at 12 months, 56% at 60 months, and 36% at 10 years. These shunts are a good alternative for patients being considered for surgery in whom other portal blood flow preserving procedures (i.e., elective shunts, devascularization with esophageal transection) are not feasible.
小口径门体分流术用于治疗门静脉高压引起的食管静脉曲张出血,这是聚四氟乙烯血管移植物发展的产物,该移植物允许使用狭窄的管腔。我们报告了10年来使用这种移植物的经验。33例肝功能良好(Child-Pugh A级)的患者接受了择期手术。这些患者的平均年龄为45岁(范围17至71岁)。29例患者患有肝硬化,1例患有门静脉纤维化,3例患有特发性门静脉高压。手术死亡率为3%,再出血率为15%。14例患者(11%)出现术后脑病,其中3例为III至IV级脑病。其余11例患者有轻度脑病,易于控制。术后血管造影显示81%的患者分流通畅,33%的患者门静脉直径缩小,6%的患者发生门静脉血栓形成。63%的患者术后生活质量良好。根据Kaplan-Meier精算方法,12个月时生存率为81%,60个月时为56%,10年时为36%。对于那些考虑手术但其他保留门静脉血流的手术(即选择性分流术、食管横断去血管化术)不可行的患者,这些分流术是一个很好的选择。