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[Advances in the development of new antitubercular agents from pyridine derivatives].

作者信息

Waisser K, Holý P, Bures O

机构信息

Katedra anorganické a organické chemie Farmaceutické fakulty, Univerzity Karlovy, Hradec Králové.

出版信息

Ceska Slov Farm. 2000 Sep;49(5):211-20.

Abstract

Tuberculosis and other mycobacterial diseases are considered to be one of the major health problems at present. Since 1985, and in particular in the 1990s, a search for new structures of antimycobacterial substances has been one of the priorities of chemotherapeutic research. Pyridine derivatives have always attracted the interest of research laboratories searching for new chemotherapeutic agents against tuberculosis. The present review paper, based on the journal Chemical Abstracts and original papers, surveys these attempts in recent fifteen years.

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