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先天性脑积水预后的一些观察(第二次报告)——关于存活病例的身体残疾(作者译)

[Some observations on prognosis in congenital hydrocephalus (second report) -with reference to the physical handicap in survival cases (author's transl)].

作者信息

Ito H, Onodera Y, Takanashi K, Tajima K, Miwa T

出版信息

No Shinkei Geka. 1975 Apr;3(4):313-22.

PMID:1107877
Abstract

The prognosis of surgically treated congenital hydrocephalus has lately proven to give a remarkably increased expectation of life for patient. However, numerous reports hve shown that the prognosis of congenital hydrocephalus have not always shown favourable turns from the viewpoints of physical and mental disability. This problem has been considered many times over the past years. But, an important problem has been left unsolved. The children of social and physical disability are most serious problem, so we attempt to obain a new interpretation about the influence factors upon the prognosis. Present report consists of follow-up studies of long surviving patients who have studied the fatty acid metabolism in the cerebrospinal fluid during postoperatively, the influeence on prognosis of complicated central nervous system malformation and discussed motor and mental disability in survival cases. Since lipids are essential factors in composing the brain tissues, quantitative composition of fatty acid inC.S.F. was determined by the method of gaschromatography using the arachidic acid as an indicator...

摘要

最近已证实,手术治疗先天性脑积水的预后能显著提高患者的预期寿命。然而,大量报告表明,从身体和精神残疾的角度来看,先天性脑积水的预后并非总是向好的方向转变。在过去几年里,这个问题已经被多次探讨。但是,一个重要问题仍未得到解决。社会和身体残疾的儿童是最严重的问题,因此我们试图对影响预后的因素获得新的解释。本报告包括对长期存活患者的随访研究,这些患者在术后研究了脑脊液中的脂肪酸代谢、复杂中枢神经系统畸形对预后的影响,并讨论了存活病例中的运动和精神残疾情况。由于脂质是构成脑组织的重要因素,脑脊液中脂肪酸的定量组成通过以花生酸为指标的气相色谱法测定……

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