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从印度传统阿育吠陀医学中获取灵感进行药物研发:以肝炎和类风湿为例。

Drug development with hints from traditional Indian Ayurveda medicine: hepatitis and rheumatoid as an example.

作者信息

Okamoto T, Hino O

机构信息

Research Laboratories, Nippon Chemiphar Co., Ltd, Misato, Saitama 341-0005, Japan.

出版信息

Int J Mol Med. 2000 Dec;6(6):613-5. doi: 10.3892/ijmm.6.6.613.

Abstract

Although many drugs have been developed by pharmaceutical companies, there are many diseases which can not be cured with these drugs. In order to overcome this problem, the combination of Western and Eastern medicine has been proposed. Ayurveda is traditional Indian medicine established B.C. and is accepted throughout the world today. Due to its effectiveness and fewer side effects, Ayurveda will provide us with many hints for drug development. In the present review, we discuss the possible application of Ayurveda in drug development taking into account the following two points, i) herbs used in Ayurveda contain many unknown active components, and ii) Ayurveda provides new therapeutic approaches. In the case of drugs for the treatment of chronic hepatitis, we get hints from active components in the herbs used in Ayurveda. For rheumatism, we obtain hints for new pharmacological approaches from this medicinal approach.

摘要

尽管制药公司已经研发出了许多药物,但仍有许多疾病无法用这些药物治愈。为了克服这一问题,人们提出了中西医结合的方法。阿育吠陀是公元前建立的传统印度医学,如今在全世界都被接受。由于其有效性和较少的副作用,阿育吠陀将为我们的药物研发提供许多启示。在本综述中,我们考虑以下两点来讨论阿育吠陀在药物研发中的可能应用:i)阿育吠陀中使用的草药含有许多未知的活性成分,ii)阿育吠陀提供了新的治疗方法。在治疗慢性肝炎的药物方面,我们从阿育吠陀中使用的草药的活性成分中获得了启示。对于风湿病,我们从这种医学方法中获得了新药理学方法的启示。

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