School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India.
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India.
J Ethnopharmacol. 2017 Feb 2;197:10-24. doi: 10.1016/j.jep.2016.09.024. Epub 2016 Sep 12.
Ayurveda entails a scientific tradition of harmonious living and its origin can be traced from ancient knowledge in Rigveda and Atharvaveda. Ayurveda is a traditional healthcare system of Indian medicine since ancient times. Several Ayurvedic medicines have been exploiting for treatment and management of various diseases in human beings. The several drugs have been developed and practiced from Ayurveda since ancient time to modern practice as 'tradition to trend'. The potential of Ayurvedic medicine needs to be explored further with modern scientific validation approaches for better therapeutic leads.
The present study was aimed to explore the various aspects of Ayurveda and inspired drug discovery approaches for its promotion and development.
We have reviewed all the literature related to the history and application of Ayurvedic herbs. Various aspects for the quality control, standardization, chemo-profiling, and metabolite fingerprinting for quality evaluation of Ayurvedic drugs. The development of Ayurvedic drugs is gaining momentum with the perspectives of safety, efficacy and quality for promotion and management of human health. Scientific documentation, process validation and several others significant parameters are key points, which can ensure the quality, safety and effectiveness of Ayurvedic drugs.
The present review highlights on the major goal of Ayurveda and their significant role in healthcare system. Ayurveda deals with several classical formulations including arka, asavas, aristas, churna, taila, vati, gutika, bhasma etc. There are several lead molecules that have been developed from the Ayurvedic herbs, which have various significant therapeutic activities. Chemo-profiling of Ayurvedic drug is essential in order to assess the quality of products. It deals with bioactive compound quantification, spurious and allied drug determination, chromatographic fingerprinting, standardization, stability and quality consistency of Ayurvedic products.
Scientific validation and the documentation of Ayurvedic drugs are very essential for its quality evaluation and global acceptance. Therapeutic efficacy of Ayurvedic herbs may be enhanced with high quality, which can be achieved by identity, purity, safety, drug content, physical and biological properties. Ayurvedic medicines need be explored with the modern scientific approaches for its validation. Therefore, an attempt has been made in the present review to highlight the crucial aspects that need to be considered for the promotion and development of Ayurvedic medicine.
阿育吠陀包含一种和谐生活的科学传统，其起源可以追溯到《梨俱吠陀》和《阿闼婆吠陀》中的古代知识。阿育吠陀是印度医学自古以来的传统医疗体系。几种阿育吠陀药物已被用于治疗和管理人类的各种疾病。自古代以来，许多药物已经从阿育吠陀发展到现代实践，即“传统到趋势”。需要进一步探索阿育吠陀药物的潜力，采用现代科学验证方法，以获得更好的治疗方法。
本研究旨在探讨阿育吠陀的各个方面，并为其推广和发展探索灵感药物发现方法。
我们综述了与阿育吠陀草药的历史和应用相关的所有文献。还综述了用于评估阿育吠陀药物质量的各个方面，包括质量控制、标准化、化学生态分析和代谢产物指纹图谱。阿育吠陀药物的发展具有安全性、有效性和质量的观点，以促进和管理人类健康。科学文件、工艺验证和其他几个重要参数是确保阿育吠陀药物质量、安全性和有效性的关键。
本综述重点介绍了阿育吠陀的主要目标及其在医疗保健系统中的重要作用。阿育吠陀涉及几种经典配方，包括阿耳卡、阿萨瓦斯、阿里斯塔、丘尔纳、泰拉、瓦蒂、古提卡、巴斯马等。已经从阿育吠陀草药中开发出几种具有各种显著治疗活性的先导分子。评估产品质量，阿育吠陀药物的化学生态分析是必不可少的。它涉及生物活性化合物定量、伪品和相关药物测定、色谱指纹图谱、标准化、稳定性和阿育吠陀产品质量一致性。
科学验证和阿育吠陀药物的文件对于其质量评估和全球接受非常重要。阿育吠陀草药的治疗功效可以通过身份、纯度、安全性、药物含量、物理和生物学特性来提高质量。需要用现代科学方法来验证阿育吠陀药物。因此，本综述试图强调促进和发展阿育吠陀医学需要考虑的关键方面。
