Dimmick J, Mahmood K, Altshuler G
Obstet Gynecol. 1976 Jan;47(1):56-62.
It has been argued that fetal and placental infections decrease the incidence of hyaline membrane disease (HMD). However, others contend that this is not so. We performed a rigidly controlled clinicopathologic investigation of one group of infants with evidence of severe antenatal infection compared with another group free of infection. This study shows that placental infection correlated positively with neonatal sepsis and that in this series of patients neither infection nor prolonged rupture of membranes is associated with a decrease of HMD. Our data do not support the proposal that antenatal infections protect the neonate against later development of HMD.
有人认为胎儿和胎盘感染会降低透明膜病（HMD）的发病率。然而，其他人则认为并非如此。我们对一组有严重产前感染证据的婴儿与另一组无感染的婴儿进行了严格对照的临床病理研究。这项研究表明，胎盘感染与新生儿败血症呈正相关，并且在这组患者中，感染和胎膜早破均与HMD的减少无关。我们的数据不支持产前感染可保护新生儿免于日后发生HMD这一观点。
