Plotkina N S, Krasovskaia S B, Virnik A D
Polim Med. 1975;5(3):213-21.
The study concerned antibacterial properties of the ftorlon threads obtained from acetone or dimethylformamide polymer solution containing antibacterial derivatives of 5-nitrofuran added which were known to be active against the germs most commonly causing the postoperative infection including Staphylococci, Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris and Candida type fungi. Basing of the laboratory test following the method of infected medium and suspension method it was found that the best effects were obtained when using threads produced from the acetone polymer solution added with beta-(5-nitrofuryl-2)-acroleine and those containing furazolidone obtained from acetone or dimethylformamide polymer solution. Antibacterial properties of the ftorlon threads did not change upon autoclaving, gamma irradiation and prolonged storage.
该研究关注了从含有添加了5-硝基呋喃抗菌衍生物的丙酮或二甲基甲酰胺聚合物溶液中获得的氟纶线的抗菌性能，已知这些衍生物对最常引起术后感染的病菌具有活性，包括葡萄球菌、大肠杆菌、铜绿假单胞菌、普通变形杆菌和念珠菌属真菌。基于采用感染培养基法和悬浮法的实验室测试，发现使用添加了β-(5-硝基呋喃基-2)-丙烯醛的丙酮聚合物溶液制成的线以及从丙酮或二甲基甲酰胺聚合物溶液中获得的含有呋喃唑酮的线时，效果最佳。氟纶线的抗菌性能在高压灭菌、伽马射线辐照和长期储存后不会改变。
