Jakobovits R, Soderland S G, Taira R K, Brinkley J F
Structured Reporting Systems, Seattle, WA, USA.
Proc AMIA Symp. 2000:374-8.
Recent advances in tools for scientific data acquisition, visualization, and analysis have lead to growing information management problems for medical research laboratories. An exponential increase in the volume of data, combined with a proliferation of heterogeneous formats and autonomous systems, has driven the need for flexible and powerful Experiment Management Systems (EMS). This paper provides a detailed analysis of the informatics requirements of an EMS, and proposes a new type of middleware called an EMS-Building Environment (EMSBE), which enables the rapid development of web-based systems for managing laboratory data and workflow. We describe the Web-Interfacing Respository Manager (WIRM), an open-source application server for building customizable experiment management systems. WIRM is being used to manage several ongoing experiments, including a natural language processor of radiological findings, and an interdisciplinary project for studying brain function.
科学数据采集、可视化和分析工具的最新进展给医学研究实验室带来了日益严重的信息管理问题。数据量呈指数级增长,再加上异构格式和自主系统的大量涌现,催生了对灵活且强大的实验管理系统(EMS)的需求。本文详细分析了EMS的信息学需求,并提出了一种新型中间件,称为EMS构建环境(EMSBE),它能够快速开发用于管理实验室数据和工作流程的基于网络的系统。我们描述了网络接口存储库管理器(WIRM),这是一个用于构建可定制实验管理系统的开源应用服务器。WIRM正被用于管理多个正在进行的实验,包括一个放射学检查结果的自然语言处理器,以及一个研究脑功能的跨学科项目。