BouzBouz S, Popkin ME, Cossy J
Laboratoire de Chimie Organique associe au CNRS, ESPCI, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
Org Lett. 2000 Nov 2;2(22):3449-51. doi: 10.1021/ol0057434.
Optically active cyclopentadienyldialkoxyallyltitanium complexes have been employed for the desymmetrization of meso-dialdehydes. Allylation of these dialdehydes and subsequent oxidation afford chiral lactones with good diastereoselectivity and excellent enantioselectivity.
光学活性的环戊二烯基二烷氧基烯丙基钛配合物已被用于内消旋二醛的去对称化反应。这些二醛的烯丙基化反应以及随后的氧化反应可得到具有良好非对映选择性和优异对映选择性的手性内酯。
