Wielgoś M, Bablok L, Fracki S, Rokicki T, Marianowski L
I Katedry i I Kliniki Połoznictwa i Ginekologii AM w Warszawie.
Ginekol Pol. 2000 Sep;71(9):1042-6.
The aim of this study was to assess the eventual impact of degenerative changes of seminiferous tubules on Doppler flow parameters in testicular vessels.
There were 12 men with degenerative changes of seminiferous tubules (diagnosed by testicular biopsy) in study group and 24 healthy men with normal semen parameters in control group. Patients' age in both groups was respectively 32.22 +/- 5.31 and 29.64 +/- 3.17 (ns). Sonographic biometry of testes volume was performed and the values of qualitative flow indices in terminal section of testicular artery were evaluated. The both groups results were compared with themselves by T-test. Also the values of qualitative flow parameters in testis after biopsy and contralateral one were compared. Additionally the correlation between vascular flow parameters and selected hormone levels (FSH, LH, T, E2 and Prl) was determined.
The mean testes volume in the study group was 10.81 +/- 3.77 cm3 and in the control one 14.42 +/- 5.42 cm3 (ns). The values of particular flow indices in both study and control group were respectively: S:D 3.20 +/- 0.95 and 2.92 +/- 0.96 (ns), PI 1.46 +/- 0.46 and 1.23 +/- 0.41 (ns), RI 0.69 +/- 0.09 and 0.66 +/- 0.08 (ns). There were no differences between flow parameters in testis after biopsy and contralateral one. Testosterone was the only hormone correlating with analyzed flow indices (S:D, PI, RI) and the correlation coefficient value was respectively 0.51, 0.49 and 0.52 (p < 0.05).
The significant influence of degenerative changes of seminiferous tubules on vascular flow in testicular artery was not observed. There were no differences between flow parameters in testis after biopsy and contralateral one. The testosterone was the only hormone significantly correlating with analyzed flow indices.
本研究旨在评估生精小管退行性变对睾丸血管多普勒血流参数的最终影响。
研究组有12名经睾丸活检诊断为生精小管退行性变的男性，对照组有24名精液参数正常的健康男性。两组患者年龄分别为32.22±5.31岁和29.64±3.17岁（无显著性差异）。进行睾丸体积的超声生物测量，并评估睾丸动脉末端定性血流指数值。两组结果通过t检验进行自身比较。此外，还比较了活检侧与对侧睾丸定性血流参数值。另外，确定了血管血流参数与选定激素水平（促卵泡激素、促黄体生成素、睾酮、雌二醇和泌乳素）之间的相关性。
研究组平均睾丸体积为10.81±3.77cm³，对照组为14.42±5.42cm³（无显著性差异）。研究组和对照组各血流指数值分别为：收缩期峰值流速与舒张末期流速比值（S:D）3.20±0.95和2.92±0.96（无显著性差异），搏动指数（PI）1.46±0.46和1.23±0.41（无显著性差异），阻力指数（RI）0.69±0.09和0.66±0.08（无显著性差异）。活检侧与对侧睾丸血流参数无差异。睾酮是唯一与分析的血流指数（S:D、PI、RI）相关的激素，相关系数值分别为0.51、0.49和0.52（p<0.05）。
未观察到生精小管退行性变对睾丸动脉血流有显著影响。活检侧与对侧睾丸血流参数无差异。睾酮是唯一与分析的血流指数显著相关的激素。
