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[增殖细胞核抗原(PCNA)抗原在宫颈癌细胞增殖活性中的表达]

[Expression of PCNA antigen in cellular proliferative activity of cervical carcinoma].

作者信息

Lenczewski A, Terlikowski S, Sulkowska M, Famulski W, Dobrzycka B, Sulkowski S, Musiatowicz B, Kulikowski M

机构信息

Kliniki Ginekologii i Połoznictwa Septycznego, Białymstoku.

出版信息

Ginekol Pol. 2000 Sep;71(9):1164-8.

PMID:11082996
Abstract

The proliferative activity of cervical carcinoma was examined using proliferating cell nuclear antigen (PCNA) staining. Labelling index (LI) have been counted in sections of routinely processed paraffin embedded tissue blocks. Significant variation in PCNA LI were observed between study groups (p < 0.0235). The results obtained indicate that the evaluation of proliferative activity of cells expressed by high PCNA LI is assessed with worse prognosis.

摘要

采用增殖细胞核抗原(PCNA)染色法检测宫颈癌的增殖活性。在常规处理的石蜡包埋组织块切片中计数标记指数(LI)。研究组之间观察到PCNA LI存在显著差异(p < 0.0235)。所得结果表明,通过高PCNA LI表达的细胞增殖活性评估提示预后较差。

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