[核仁组织区（NORs）表达分析中卵巢上皮性肿瘤的异质性]
[Heterogeneity of ovarian epithelial tumors in analysis of nucleolar organizer regions (NORs) expression].
作者信息
Terlikowski S, Lenczewski A, Sulkowska M, Famulski W, Sulkowski S, Musiatowicz B, Kulikowski M
机构信息
Zakładu Anatomii Patologicznej Akademii Medycznej w Białymstoku.
出版信息
Ginekol Pol. 2000 Sep;71(9):1194-7.
Nonhistone proteins associated with the nucleolar organizer regions (NORs) can be visualized by a silver-staining technique on paraffin-embedded tissues. The number of black dots (AgNORs) appearing on the nuclei are thought to reflect cell differentiation and can be used as a measurement of cellular proliferative activity. In this study we tested AgNOR staining in ovarian epithelial tumors to evaluate its diagnostic potential in distinguishing between borderline tumors and carcinomas.
与核仁组织区（NORs）相关的非组蛋白可通过石蜡包埋组织上的银染技术进行可视化。细胞核上出现的黑点数量（AgNORs）被认为反映了细胞分化情况，可作为细胞增殖活性的一种度量。在本研究中，我们对卵巢上皮性肿瘤进行了AgNOR染色测试，以评估其在区分交界性肿瘤和癌方面的诊断潜力。
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