Matsuo T, Colt H G
Interventional Pulmonary Section of the Pulmonary and Critical Care Medicine Division, University of California-San Diego Medical Center, La Jolla, CA 92037-0976, USA.
Chest. 2000 Nov;118(5):1455-9. doi: 10.1378/chest.118.5.1455.
To determine whether routine scheduling of surveillance flexible fiberoptic bronchoscopy is warranted within 2 to 3 months after silicone stent insertion for central airway obstruction.
Retrospective cohort study.
University medical center.
All patients with silicone stents placed for benign or malignant tracheobronchial obstruction during a 3-year period.
Incidence of stent-related complications, new respiratory symptoms, and need for therapeutic bronchoscopic intervention were noted in patients undergoing surveillance bronchoscopy (SFFB) and emergency bronchoscopy (EFFB), defined as flexible fiberoptic bronchoscopy prompted by onset of new symptoms before the date of scheduled SFFB.
One hundred one silicone stents were inserted in 88 patients (47 with cancer, 41 with benign disease). Eighteen patients died within 2 months and had no bronchoscopy. Seventy patients underwent either SFFB or EFFB. Stent-related complications were detected in 9 of 31 asymptomatic patients (29%) undergoing SFFB; all had received tumor-specific therapy after stent insertion (in 7 of 8 patients [88%] reporting new respiratory symptoms at the time of SFFB, and in 26 of 31 patients [84%] undergoing EFFB). Overall, stent-related complications were detected in nine asymptomatic patients (10% of total), of which only four patients (5% of total, but 13% of all asymptomatic patients) required therapeutic interventions.
Routine SFFB within 2 to 3 months after stent insertion did not detect a high incidence of stent-related complications among patients without new respiratory symptoms.
确定对于因中央气道阻塞而植入硅酮支架的患者,在植入后2至3个月内进行常规的监测性可弯曲纤维支气管镜检查是否必要。
回顾性队列研究。
大学医学中心。
在3年期间内所有因良性或恶性气管支气管阻塞而植入硅酮支架的患者。
记录接受监测性支气管镜检查(SFFB)和急诊支气管镜检查(EFFB)的患者中与支架相关的并发症发生率、新出现的呼吸道症状以及治疗性支气管镜干预的需求,其中EFFB定义为在预定的SFFB日期之前因新症状发作而进行的可弯曲纤维支气管镜检查。
88例患者共植入了101个硅酮支架(47例为癌症患者,41例为良性疾病患者)。18例患者在2个月内死亡,未进行支气管镜检查。70例患者接受了SFFB或EFFB。在31例接受SFFB的无症状患者中,有9例(29%)检测到与支架相关的并发症;所有这些患者在植入支架后均接受了肿瘤特异性治疗(在SFFB时报告有新呼吸道症状的8例患者中有7例[88%],在接受EFFB的31例患者中有26例[84%])。总体而言,9例无症状患者(占总数的10%)检测到与支架相关的并发症,其中只有4例患者(占总数的5%,但占所有无症状患者的13%)需要进行治疗性干预。
在植入支架后2至3个月内进行常规SFFB,在没有新呼吸道症状的患者中未检测到与支架相关并发症的高发生率。