Obel O, Coltart D J, Signy M
Cardiothoracic Centre, Guy's and St Thomas Hospital NHS Trust, London, UK.
Heart. 2000 Dec;84(6):E13. doi: 10.1136/heart.84.6.e13.
Half of all patients with carcinoid syndrome develop cardiac involvement. Patients who have cardiac involvement have a significantly worse prognosis than those without, and death can occur directly as a result of cardiac involvement. A case of carcinoid syndrome in a 38 year old woman with lesions in the liver, who presented with right sided valvar abnormalities, a dilated right ventricle, and right ventricular pressure overload, is presented. In order to palliate the patient's symptoms and to decrease right sided pressures before major abdominal surgery, balloon pulmonary valvuloplasty was performed at the time of cardiac catheterisation. This resulted in a reduction in the pulmonary gradient and right ventricular pressure. Following the procedure, the patient's symptoms were completely relieved. She went on to laparotomy where the lesions in the liver were excised without complication.
类癌综合征患者中有一半会出现心脏受累。出现心脏受累的患者预后明显比未受累者差,且死亡可能直接由心脏受累导致。本文报告了一例38岁患有肝脏病变的类癌综合征女性病例,该患者表现为右侧瓣膜异常、右心室扩张和右心室压力过载。为了在进行大型腹部手术前缓解患者症状并降低右侧压力,在心脏导管插入术时进行了球囊肺动脉瓣成形术。这使得肺动脉梯度和右心室压力降低。术后,患者症状完全缓解。她随后接受了剖腹手术,肝脏病变被切除,未出现并发症。