肺炎衣原体初次感染期间的细胞介导免疫反应。
Cell-mediated immune response during primary Chlamydia pneumoniae infection.
作者信息
Halme S, Latvala J, Karttunen R, Palatsi I, Saikku P, Surcel H M
机构信息
National Public Health Institute, University of Oulu, Oulu, Finland.
出版信息
Infect Immun. 2000 Dec;68(12):7156-8. doi: 10.1128/IAI.68.12.7156-7158.2000.
Abstract
The development of Chlamydia pneumoniae-specific cell-mediated immunity was studied during a primary C. pneumoniae infection. The immune response was detected as positive lymphocyte proliferation and secretion of interferon gamma. C. pneumoniae-induced activation of both CD4(+) and CD8(+) T cells was detected in the early phase of infection, but activation of only CD4(+) T cells was detected in the later stage.
摘要
在肺炎衣原体初次感染期间，对肺炎衣原体特异性细胞介导免疫的发展进行了研究。免疫反应通过淋巴细胞增殖阳性和γ干扰素分泌来检测。在感染早期检测到肺炎衣原体诱导的CD4(+)和CD8(+) T细胞均被激活，但在后期仅检测到CD4(+) T细胞被激活。
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