González López M, del Pino De La Fuente A, García Martín F J, Calbo Torrecillas F, Obando Santaella I, Campos J, Martínez Valverde A
Departamento de Pediatría, Hospital Materno Infantil de Málaga, Madrid.
An Esp Pediatr. 2000 Oct;53(4):369-71.
We report an immunocompetent 5-month-old boy with Haemophilus influenzae type f (Hif) meningitis. The patient had previously been immunized with two doses of Hib conjugate vaccine (PRP-T). Vaccination failure was initially suspected based on Gram stain report. The results of culture identified a non-b Haemophilus influenzae capsular serotype (Hif).Non-Hib serotypes should be considered as potential pathogenic agents in children under the age of 5 years with invasive diseases. An adequate epidemiological surveillance system would be helpful in detecting the role of these non-b Hif serotypes as significant pathogens, which appear to be on the increase.
我们报告了一名5个月大的免疫功能正常男孩,他患有f型流感嗜血杆菌(Hif)脑膜炎。该患者之前已接种过两剂b型流感嗜血杆菌结合疫苗(PRP-T)。最初根据革兰氏染色报告怀疑疫苗接种失败。培养结果鉴定出一种非b型流感嗜血杆菌荚膜血清型(Hif)。对于5岁以下患有侵袭性疾病的儿童,非b型流感嗜血杆菌血清型应被视为潜在的病原体。一个完善的流行病学监测系统将有助于检测这些非b型Hif血清型作为重要病原体的作用,而它们的出现似乎呈上升趋势。